The Department of Organic Chemistry started in 2009 offers 2-year M.Sc. Chemistry (Organic chemistry specialization) with an intake of 36 students. Admission into these courses is based on Rank in Andhra University Common Entrance Test, AUCET.

Professors L.S.A. Dikshitulu and P.V. Subba Rao, renowned teachers and researchers of the Department of Chemistry, Andhra University, Prof. P. Rajaganapathi, Retired Professor, APES and Dr. M. Bapuji, Retd. Senior Scientist, CSIR-Institute of Minerals and Materials Technology (CSIR-IMMT), Bhubaneswar Prof. A. Nageswara Rao, Retired Professor, Department of Physical & Nuclear Chemistry, Former Director, School of Chemistry, Andhra University, as founder Professors established the Department and they are adored by all for the rich traditions and laboratory practices currently in vogue. Prof. (Mrs.) P. Umadevi, Retd. Professor of Organic Chemistry, GITAM (Deemed to be University), NET/SET qualified Assistant Professors, S.S.R.S.S.N. Murty, Dr. A. Karteek Rao, Dr V. Govinda, Dr. K. V. Padmavathi, Mrs. Ch. VRT Hema are currently working in the Department. The department focuses both on teaching and research in different areas of chemistry (Synthetic organic chemistry, natural products chemistry, Drug discovery, computational Chemistry, and study of reactions of metal complexes). The department is equipped with state of the art research and library facilities. The department encourages students to develop and enhance their scientific passion and publish their results. The department also conducts national seminars, workshops, and guest lecturers to give a focus on the emerging fields of research to our students.

The laboratories are well equipped with fume hood and efficient exhaust systems. The best practice, the department can boast of, is collection of the water collected in AC units. Humidity in the air is condensed in AC Units resulting in this water. This water with near zero conductivity is equivalent to distilled water and is used directly in the laboratories. Sometimes this is also passed through Ion-Exchanger and used. Each laboratory has a distilled water storage facility of 1200 litres. Final year students are given good training in thin layer and column chromatographic techniques which will be incredibly useful both for lucrative placements and research.